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KMID : 0882420060700060636
Korean Journal of Medicine
2006 Volume.70 No. 6 p.636 ~ p.642
Seroprevalence of Helicobacter pylori in health check-up subjects
Yim Jeong-Yoon

Jeong In-Kyong
Choi Su-Yeon
Kim Sun-Sin
Kim Jeong-Hun
Shin Chan-Soo
Cho Sang-Heon
Oh Byung-Hee
Kim Na-Young
Choi Seung-Ho
Park Min-Jeoung
Kim Young-Sun
Lim Seon-Hee
Choi Keong-Ran
Kim Dong-Hee
Kim Chung-Hyun
Abstract
Background : H. pylori-associated gastrointestinal diseases have been widely recognized. The aim of this study was to investigate the seropositivity of H. pylori in health check-up subjects and to find out the relating factors.

Methods : From November 2004 through June 2005, total 7,676 health check-up subjects (age ¡Ã 20) responded to the self administered questionnaires. The prevalence of H. pylori was assessed by measuring anti-H. pylori IgG antibodies.

Results : The overall seropositivity was 56.7% in 7,676 and 1,137 (14.8%) has been found to have history of H. pylori eradication therapy. The seropositivity rate of H. pylori was 61.3% (2,653) in 4,328 subjects without history of H. pylori eradication and current gastrointestinal symptoms. Seroprevalence of H. pylori was significantly lower in 20¢¦29 years old, female, high income and subjects from Seoul respectively.

Conclusion : The seropositivity of H. pylori in 2004¢¦2005 is found to be 61.3% in subjects without history of H. pylori eradication and current gastrointestinal symptoms. This seems to be lower than 66.9%, the seroprevalence rate in asymptomatic Korean population in the age of ¡Ã16 years in 1998. This decrease might be caused by improvement of socioeconomic status.(Korean J Med 70:636-642, 2006)
KEYWORD
Helicobacter pylori, Seroepidemiologic studies, Eradication
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